THP | Allopregnanolone steroid standard | AS04 041S

THP | Allopregnanolone steroid standard | AS04 041S | Gentaur UK, US & Europe Distribution

Immunogen: N/A

Host: N/A

Conjugation: N/A

Clonality: N/A

Isotype: N/A

Purity: N/A

Format: Lyophilized

Tested Application: Radioimmunoassay (RIA)

Related Products: AS04 041 | anti-allopregnanolone antibody

Recommended Dilutions: N/A

Molecular weight: N/A

Confirmed Reactivity: N/A

Predicted Reactivity: N/A

Not reactive in: N/A

Additional Information: The lyophilized powder of this standard is not soluble in water. Standard dissolving instruction: Use ethanol (99.5 %) or methanol to prepare a concentrated (stock) solution of THP standard. This solution can be stored for longer time in a sealed tube.Working solution can be used daily but needs to be changed after one month.Working solution is used to prepare standard points 0-200 pg. It needs to be dried under nitrogen before it is diluted in water based soltion, otherwise the steroid will oxidase.Following dyring, water based solution can be added to this standard.

Background: Allopregnanolone, (3alpha-hydroxy-20-oxo-5alphapregnan-11alpha-yl-carboxymethylether), also known as 3alpha, 5alpha-tetrahydroprogesterone or THP, a neuroactive steroid secreted by the mammalian ovary, exerts its anesthetic, anxiolytic, and sedative/hypnotic effects through potentiation of GABA A receptors. It is produced in the human corpus luteum and their release is stimulated by trophic hormone.

Reconstitution: N/A

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. Protect from light, Can be stored for 1 month at 4°C in a sealed tube or flask.

TAIR Nnumbre: N/A

Category: Neurobiology

Research Area: Neurobiology