Tim-2, Mouse Recombinant | P1356

Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.

P1356 | Tim-2 Mouse Recombinant DataSheet

Biomolecule/Target: Tim-2

Synonyms: TIM2; TIMD2; T Cell Immunoglobulin and Mucin Domain-containing Protein 2

Alternates names: Roof plate-specific Spondin 2, Rspo2

Taglines: SEMA4A receptor involved in the regulation of T-cell function

NCBI Gene ID #: 340419

NCBI Gene Symbol: RSPO2

Gene Source: Human

Accession #: Q6UXX9

Recombinant: Yes

Source: CHO Cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): R-Spondin-2 enhances BMP-2 mediated differentiation of MC3T3-E1 cells.

Biological activity: R-Spondin-2 enhances BMP-2 mediated differentiation of MC3T3-E1 cells.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 30.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10mM Sodium Phosphate, pH 7.5 and 150 mM NaCl.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: ASYVSNPICK GCLSCSKDNG CSRCQQKLFF FLRREGMRQY GECLHSCPSG YYGHRAPDMN RCARCRIENC DSCFSKDFCT KCKVGFYLHR GRCFDECPDG FAPLEETMEC VEGCEVGHWS EWGTCSRNNR TCGFKWGLET RTRQIVKKPV KDTILCPTIA ESRRCKMTMR HCPGGKRTPK AKEKRNKKKK RKLIERAQEQ HSVFLATDRA NQ