TIMP2 polyclonal Antibody | BS91348

TIMP2 polyclonal Antibody | BS91348 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB FC

Application Range: WB:1:500-1:2,000 FC:1:10-1:50

Background: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity) . Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TIMP2 polyclonal Antibody detects endogenous levels of TIMP2 protein.

Molecular Weight: 22 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TIMP-2, TIMP2, CSC 21K, CSC-21K, CSC21K, Metalloproteinase inhibitor 2, Metalloproteinase inhibitor 2 precursor, TIMP 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, TIMP2, Tissue Inhibitor of Metalloproteinase 2, Tissue inhibitor of metalloproteinases 2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: