TL-1A Antibody | 38-162

TL-1A Antibody | 38-162 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hTL-1A. Human TL-1A specific antibody was purified by affinity chromatography employing immobilized hTL-1A matrix.

Research Area: Chemokines & Cytokines, Immunology, Antibody Pairs

Tested Application: E, WB

Application: ELISA:
Indirect:
To detect hTL-1A by indirect ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTL-1A.
Sandwich
To detect hTL-1A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Human TL-1A as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTL-1A.
Western Blot:
To detect hTL-1A by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hTL-1A is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Lyophilized

Buffer: N/A

Concentration: N/A

Storage Condition: TL-1A antibody is stable for at least 2 years from date of receipt at -20˚C. The reconstituted antibody is stable for at least two weeks at 2-8˚C. Frozen aliquots are stable for at least 6 months when stored at -20˚C. Avoid repeated freeze-thaw cycles.

Alternate Name: TL1, TL1A, VEGI, VEGI192A, TL1, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1,

User Note: Centrifuge vial prior to opening.

BACKGROUND: TL1A is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a TNF like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. TL1A is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL 1 alpha. TL1A can activate NF kappa B and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells and may function as an angiogenesis inhibitor. TL1A is a longer variant of TL1.