TLR2 polyclonal Antibody | BS91352

TLR2 polyclonal Antibody | BS91352 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IHC FC

Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes. TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity, and, like other members of TLR family, it induces NFkB signaling upon activation.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TLR2 polyclonal Antibody detects endogenous levels of TLR2 protein.

Molecular Weight: N/A

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TIL4, TLR2, CD282, CD282 antigen, TIL 4, TIL4, TLR 2, TLR2, TLR2, Toll like receptor 2, Toll like receptor 2 precursor, Toll-like receptor 2, Toll/interleukin 1 receptor like 4, Toll/interleukin 1 receptor like protein 4, Toll/interleukin receptor like protein 4, Toll/interleukin-1 receptor-like protein 4,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: