TLR5 Polyclonal Antibody | E-AB-10872

TLR5 Polyclonal Antibody | E-AB-10872 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: FLJ10052, MGC126430, MGC126431, SLEB1, TIL 3, TIL3, TLR 5, Tlr5, TLR5, Toll like receptor 5, Toll like receptor 5 precursor, Toll-like receptor 5, Toll/interleukin 1 receptor like protein 3, Toll/interleukin-1 receptor-like protein 3

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology

Background: This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human TLR5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A