TLX2 Antibody | 7373

TLX2 Antibody | 7373 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2.
The immunogen is located within amino acids 20 - 70 of TLX2.

Research Area: Stem Cell

Tested Application: E, WB, IHC-P, IF

Application: TLX2 antibody can be used for detection of TLX2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Specificiy: TLX2 antibody is predicted to not cross-react with other TLX proteins.

Positive Control 1: Cat. No. 1463 - Rat Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 31 kDa
Observed: 30 kDa

Validation: N/A

Isoform: N/A

Purification: TLX2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TLX2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TLX2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: TLX2 Antibody: NCX, HOX11L1, NCX, T-cell leukemia homeobox protein 2, Homeobox protein Hox-11L1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1) , is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.