Description
TMED10 Polyclonal Antibody | E-AB-19178 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: 1110014C03Rik , 21 kDa transmembrane trafficking protein, 21 kDa transmembrane-trafficking protein, MGC102351, p23, p24 family protein delta 1, p24 family protein delta-1, p24(DELTA), p24delta, p24delta1, S31I125, S31III125, TMED 10, Tmed10, TMEDA, Tmp 21 I, Tmp 21, Tmp 21 I, Tmp-21-I, Transmembrane emp24 domain containing protein 10, Transmembrane emp24 domain-containing protein 10, Transmembrane emp24-like trafficking protein 10 (yeast), Transmembrane protein Tmp21, Transmembrane trafficking protein 21kD
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Neuroscience, Signal transduction
Background: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Concentration: 1.14 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human TMED10
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 25 kDa
Molecular Weight(Observed): Refer to figures