TNFAIP8L2 polyclonal Antibody | BS72144

TNFAIP8L2 polyclonal Antibody | BS72144 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Application: WB,IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: TNFα-IP 8L2 (tumor necrosis factor, α-induced protein 8-like 2), also known as TIPE2, is a 184 amino acid protein that shares 94% identity with its mouse counterpart and belongs to the TNFAIP8 family. Expressed in spleen, thymus, small intestine and lymph node with lower levels present in colon, lung and skin, TNFα-IP 8L2 plays a role in maintaining immune homeostasis, specifically by acting as a negative regulator of both innate and adaptive immunity. In addition, TNFα-IP 8L2 functions as a negative regulator of T cell receptor function and is thought to promote FAS-induced apoptosis. The gene encoding TNFα-IP 8L2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TNFAIP8L2 polyclonal Antibody detects endogenous levels of TNFAIP8L2 protein.

Molecular Weight: 20kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TIPE2

Immunogen: Recombinant protein of human TNFAIP8L2

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: