TNFRSF13C Polyclonal Antibody | E-AB-16646

TNFRSF13C Polyclonal Antibody | E-AB-16646 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: B cell activating factor receptor, B-cell-activating factor receptor, BAFF R, BAFF receptor, BAFF-R, BAFFR, BLyS receptor 3, BlySR3, BR 3, BR3, BROMIX, CD 268, CD268, CD268 antigen, CVID4, MGC138235, OTTHUMP00000028746, Prolixin, TNFRSF 13C, Tnfrsf13c, TR13C, Tumor necrosis factor receptor subunit member 13C, Tumor necrosis factor receptor superfamily member 13C

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal transduction

Background: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human TNFRSF13C

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A