TNFSF4 polyclonal Antibody | BS61020

TNFSF4 polyclonal Antibody | BS61020 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The Ox40 ligand, Ox40L (also designated gp34), is a type II membrane protein, due to the absence of a signal peptide. Ox40L, a member of the tumor necrosis factor (TNF) superfamily, is a costimulatory molecule involved in dendritic cell:T cell interactions, T cell homing and B cell activation. Engagement of Ox40L with its receptor, Ox40, delivers a strong costimulatory signal to effector T cells. Ox40L is found preferentially on activated B cells and its receptor, Ox40, is a member of the tumor necrosis factor receptor (TNFR) family that is expressed on activated T cells. Ox40L plays a critical role in antigen-specific T cell responses in vivo and in both the priming and effector phases of T cell activation when expressed on antigen-presenting cells (APCs) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TNFSF4 polyclonal Antibody detects endogenous levels of TNFSF4 protein.

Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; CD252; TNFSF4; TXGP1

Immunogen: A synthetic peptide corresponding to residues in Human TNFSF4.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: