TNK1 Antibody (C-term) [APR33251G]

TNK1 Antibody (C-term) [APR33251G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 554-588 amino acids from the C-terminal region of human TNK1.

Cellular Localisation: Cytoplasm. Membrane; Peripheral membrane protein

Molecular Weight: 72468

Clone: Polyclonal

Gene Name: TNK1 {ECO:0000312|EMBL:AAC99412.1}

Gene ID: 8711

Function: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.

Summary: Tissue Location: Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000- 1:2000

Synonyms: Non-receptor tyrosine-protein kinase TNK1, CD38 negative kinase 1, TNK1 {ECO:0000312|EMBL:AAC994121}