TNP2 Antibody (C-term) [APR31021G]

TNP2 Antibody (C-term) [APR31021G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TNP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the C-terminal region of human TNP2.

Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:P11378}. Chromosome {ECO:0000250|UniProtKB:P11378}. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity) . Nuclear import is ATP-dependent and nucleolar localization requires the protein to be phosphorylated (By similarity) . {ECO:0000250|UniProtKB:P11101, ECO:0000250|UniProtKB:P11378}

Molecular Weight: 15641

Clone: Polyclonal

Gene Name: TNP2

Gene ID: 7142

Function: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

Summary: Tissue Location: Expressed by spermatids (at protein level) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Nuclear transition protein 2, TP-2, TP2, TNP2