TNPO3 polyclonal Antibody | BS91365

TNPO3 polyclonal Antibody | BS91365 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IF IHC

Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: The Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: TNPO3 polyclonal Antibody detects endogenous levels of TNPO3 protein.

Molecular Weight: 104 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Imp12, TRN-SR, TNPO3, IPO12, TNPO 3, Imp12, Importin 12, Importin-12, IPO12, MTR10A, TNPO3, TNPO3, Transportin 3, Transportin SR, Transportin-3, Transportin-SR, TRN SR, TRN-SR, TRN-SR2, TRNSR,

Immunogen: N/A

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: