TOR | Target of rapamycin | AS12 2608

TOR | Target of rapamycin | AS12 2608 | Gentaur UK, US & Europe Distribution

Immunogen: KLH-conjugated synthetic peptide derived from Arabidopsis thaliana TOR protein sequence, UniProt: Q9FR53, TAIR: AT1G50030

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Immunogen affinity purified serum in PBS pH 7.4.

Format: Lyophilized

Tested Application: Western blot (WB)

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Recommended Dilutions: 1 : 5000 (WB)

Molecular weight: 279 kDa

Confirmed Reactivity: Arabidopsis thaliana, Zea mays

Predicted Reactivity: Glycne max, Nicotiana tabacum, Oryza sativa, Physcomitrium patens, Populus trichocarpa, Setaria italica, Solanum tuberosum, Sorghum bicolor, Vitis vinifera Species of your interest not listed? Contact us

Not reactive in: Chlamydomonas reinhardtii

Additional Information: TOR is a subjected to post-translational modifications (ubiquitination and phosphorylation), which can change the migration pattern in SDS gel

Background: TOR (Target of rapamycin) is an essential cell growth regulator that controls development from early embryo to seed production in response to nutrient availability in envoronmental stress conditions. It belongs to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR is expressed in embryos, endosperm and meristems. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.

Reconstitution: For reconstitution add 50 µl of sterile water

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: AT1G50030

Category: Signal transduction

Research Area: Cell Signaling