TRAFD1 Antibody (C-term) [APR04190G]

TRAFD1 Antibody (C-term) [APR04190G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TRAFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-569 amino acids from the C-terminal region of human TRAFD1.

Cellular Localisation: N/A

Molecular Weight: 64841

Clone: Polyclonal

Gene Name: TRAFD1

Gene ID: 10906

Function: Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: TRAF-type zinc finger domain-containing protein 1, Protein FLN29, TRAFD1, FLN29