Tranylcypromine Hemisulfate | 1816

An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC₅₀ <2 µM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021 (Cat. No. 1677-5, 25), causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4.

Tranylcypromine Hemisulfate is an inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC₅₀ <2 µM for BHC110/LSD1).

1816 | Tranylcypromine Hemisulfate DataSheet

Alternate Name/Synonyms: Trans (±)-2-Phenylcyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA

Appearance: White solid

Formulation: N/A

CAS Number: 13492-01-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₁N.1/2H₂SO₄

Molecular Weight: 182.2

Cell-Permeable?: Yes

Purity: ≥99% by TLC

Solubilities: H₂O (25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A Lysine-Specific Demethylase 1 (LSD1) inhibitor

MDL Number: MFCD00079222

PubChem CID: 6852410

SMILES: C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O

InChi: InChI=1S/C9H11N.H2O4S/c10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h1-5,8-9H,6,10H2;(H2,1,2,3,4)/t8-,9+;/m0./s1

InChi Key: BTHVHSMCHJCPFU-OULXEKPRSA-N