TRBP1 Antibody | 4011

TRBP1 Antibody | 4011 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: TRBP1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1.
The immunogen is located within amino acids 1310 - 1360 of TRBP1.

Research Area: Infectious Disease

Tested Application: E, WB

Application: TRBP1 antibody can be used for detection of TRBP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1212 - 3T3 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: TRBP1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TRBP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TRBP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: TRBP1 Antibody: TRM3, TRP185, TRP-185, TRM3, Probable methyltransferase TARBP1, TAR RNA-binding protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TRBP1 Antibody: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1α (EF-1α) , polypyrimidine tract-binding protein (PTB) , and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB) . TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.