TRIP4 Polyclonal Antibody | E-AB-40162

TRIP4 Polyclonal Antibody | E-AB-40162 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Activating signal cointegrator 1, ASC 1, ASC-1, HsT17391, Thyroid hormone receptor interactor 4, Thyroid receptor interacting protein 4, Thyroid receptor-interacting protein 4, TR-interacting protein 4, TRIP 4, TRIP-4, Trip4, TRIP4, ZC2HC5, Zinc finger C2HC5 type

Application: WB, IHC

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant human Activating signal cointegrator 1 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 66 kDa

Molecular Weight(Observed): 66 kDa