Trk B (phospho Tyr706/Tyr707) Antibody | 79-869

Trk B (phospho Tyr706/Tyr707) Antibody | 79-869 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Trk B (phospho Tyr706/Tyr707) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y (p) -Y (p) -R-V) derived from Human Trk B.

Research Area: Phospho-Specific

Tested Application: IHC

Application: N/A

Specificiy: The antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 706 and tyrosine 707.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 91 kDa

Validation: N/A

Isoform: N/A

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/mL

Storage Condition: Store antibody at -20˚C for up to one year.

Alternate Name: Trk-B, NTRK2, GP145-TrkB

User Note: N/A

BACKGROUND: Receptor for brain-derived neurotrophic factor (BDNF) , neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.