TrkB | Tyrosine Kinase Receptor B | AS13 2697

TrkB | Tyrosine Kinase Receptor B | AS13 2697 | Gentaur UK, US & Europe Distribution

Immunogen: Extracellular domain of glycosylated mouse TrkB protein produced in CHO cells was used as the immunogen, As shown for similar antisera, it is anticipated that this antibody will block the TrkB receptor binding of corresponding neurotrophin ligand,

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum

Format: Lyophilized

Tested Application: ELISA (ELISA), Immunohistochemistry (IHC)

Related Products: N/A

Recommended Dilutions: 1 : 10 000 (1-site ELISA), 1 : 1000-1 : 3000 (IHC), Optimal dilutions/concentrations should be determined by the end user

Molecular weight: N/A

Confirmed Reactivity: Rat, Mouse

Predicted Reactivity: N/A

Not reactive in: N/A

Additional Information: N/A

Background: TrkB is a member of the neurotrophic tyrosine receptor kinase family. It is a membrane-bound receptor and upon neurotrophin binding, it phosphorylates itself as well as MAPK pathways members. TrkB is the receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . It is Involved in the development and/or maintenance of the nervous system.

Reconstitution: For reconstitution add 100 µl of sterile water

Storage: After reconstitution keep aliquots at -20ºC for a higher stability. and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

TAIR Nnumbre: N/A

Category: Neurobiology

Research Area: Neurobiology