TRPM2 polyclonal Antibody | BS7930

TRPM2 polyclonal Antibody | BS7930 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB,IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD (+) ), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TRPM2 polyclonal Antibody detects endogenous levels of TRPM2 protein.

Molecular Weight: ~ 171 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: EREG 1; EREG1; Estrogen responsive element associated gene 1; Estrogen responsive element associated gene 1 protein; Estrogen-responsive element-associated gene 1 protein; KNP 3; KNP3; Long transient receptor potential channel 2; LTRPC 2; LTrpC-2; LTRPC2; MGC133383; NUDT9H; NUDT9L1; putative Ca2+ channel protein; transient receptor potential cation channel subfamily M member 2; Transient receptor potential channel 7; TRPC 7; TRPC7; TRPM 2; Trpm2; TRPM2_HUMAN;

Immunogen: Recombinant full length Human TRPM2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: