TRPM5 Polyclonal Antibody | E-AB-12915

TRPM5 Polyclonal Antibody | E-AB-12915 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 9430099A16Rik, Long transient receptor potential channel 5, LTrpC-5, LTrpC5, MLSN1 and TRP related gene 1, MLSN1 and TRP related gene 1 protein, MLSN1 and TRP-related, MLSN1- and TRP-related gene 1 protein, MTR1, Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5, Transient receptor potential cation channel subfamily M member 5, Transient receptor potential cation channel, subfamily M, member 5, Trpm5, TRPM5 transient receptor potential cation channel, subfamily M, member 5, TRPM5

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Neuroscience

Background: This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human TRPM5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 131 kDa

Molecular Weight(Observed): N/A