223

TRPV1 Antibody | 7179

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SKU:
223-7179-GEN
NULL341.00 - NULL647.00

Description

TRPV1 Antibody | 7179 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Guinea pig: (81%) , Mouse: (75%)

Immunogen: Rabbit polyclonal TRPV1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TRPV1.
The immunogen is located within the last 50 amino acids of TRPV1.

Research Area: Signal Transduction

Tested Application: E, WB

Application: TRPV1 antibody can be used for detection of TRPV1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1204 - K562 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 92 kDa

Validation: N/A

Isoform: N/A

Purification: TRPV1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TRPV1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TRPV1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: TRPV1 Antibody: VR1, VR1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, TrpV1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TRPV1 Antibody: TRPV1 is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons. TRPV1 is a non-selective cation channel that is structurally related to members of the TRP family of ion channels such as TRPC3 and TRPC6. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

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