TSSK4 Antibody (C-term) [APR30754G]

TSSK4 Antibody (C-term) [APR30754G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TSSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human TSSK4.

Cellular Localisation: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9D411}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9D411}. Note=In spermatozoa, present in the sperm head and in the flagellum. {ECO:0000250|UniProtKB:Q9D411}

Molecular Weight: 37454

Clone: Polyclonal

Gene Name: TSSK4 (HGNC:19825)

Gene ID: 283629

Function: Serine/threonine kinase which is involved in male germ cell development and in mature sperm function (By similarity) . May be involved in the Cre/Creb signaling pathway (By similarity) . Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells (PubMed:15964553) . Phosphorylates CREM on 'Ser-116' in vitro (By similarity) . Phosphorylates ODF2 on 'Ser-95' (By similarity) .

Summary: Tissue Location: Expressed only in the testis.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, IF

Dilution: WB--1:1000 IHC-P--1:100~500 IF--1:10~50

Synonyms: Testis-specific serine/threonine-protein kinase 4, TSK-4, TSSK-4, Testis-specific kinase 4, Serine/threonine-protein kinase 22E, TSSK4, C14orf20, STK22E, TSSK5