TTC11 polyclonal Antibody | BS91382

TTC11 polyclonal Antibody | BS91382 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IF IHC

Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: Fis1 localizes to the outer mitochondrial membrane and, along with dynamin-related protein (Drp1), participates in mitochondrial fission. Fission and fusion mechanisms regulate mitochondrial morphology within the cell. Fission frequency is determined by the level of Fis1 molecules at the mitochondrial surface. Fis1 contains a C-terminal domain, which is required for mitochondrial localization, and an N-terminal domain, which is necessary for mitochondrial fission. Fragmentation of the mitochondrial network by Fis1 leads to cytochrome c release and apoptosis. The mitochondrial fission mechanisms may be involved in positively and negatively regulating apoptosis.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: TTC11 polyclonal Antibody detects endogenous levels of TTC11 protein.

Molecular Weight: 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: hFis1, TPR repeat protein 11, FIS1, TTC11, 2010003O14Rik, CGI 135, CGI135, FIS 1, FIS1, Fis1 homolog, FIS1, S. cerevisiae, homolog of, FIS1, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae), Fission 1 (mitochondrial outer membrane) homolog (yeast), Fission 1 (mitochondrial outer membrane) homolog, Fission 1 homolog, H NH0132A01.6, hFis 1, hFis1, Mitochondrial fission 1 protein, mitochondrial fission molecule, Tetratricopeptide repeat domain 11, Tetratricopeptide repeat protein 11, TPR repeat protein 11, TTC 11,

Immunogen: N/A

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: