TTC5 Antibody (C-term) [AMM08699G]

TTC5 Antibody (C-term) [AMM08699G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TTC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the C-terminal region of human TTC5.

Cellular Localisation: Nucleus. Cytoplasm. Note=Phosphorylation at Ser- 203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm.

Molecular Weight: 48928

Clone: Polyclonal

Gene Name: TTC5

Gene ID: 91875

Function: Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Tetratricopeptide repeat protein 5, TPR repeat protein 5, Stress-responsive activator of p300, Strap, TTC5