TUFM Antibody (C-term) [APR31040G]

TUFM Antibody (C-term) [APR31040G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TUFM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-370 amino acids from the C-terminal region of human TUFM.

Cellular Localisation: Mitochondrion.

Molecular Weight: 49542

Clone: Polyclonal

Gene Name: TUFM

Gene ID: 7284

Function: Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Elongation factor Tu, mitochondrial, EF-Tu, P43, TUFM