TUG-891 | B2285

TUG-891 is a potent GPR120 (free fatty acid receptor 4; FFAR4) agonist (pEC₅₀ values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors (pEC₅₀ = 4.19 for FFA1; displays no activity at FFA2 or FFA3).

TUG-891 is a potent GPR120 (free fatty acid receptor 4; FFAR4) agonist (pEC₅₀ values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors (pEC₅₀ = 4.19 for FFA1; displays no activity at FFA2 or FFA3).

B2285 | TUG-891 DataSheet

Alternate Name/Synonyms: 3-(4-((4-Fluoro-4-methyl-[1,1-biphenyl]-2-yl)methoxy)phenyl)-propanoic acid, 4-[(4-Fluoro-4′-methyl[1,1′-biphenyl]-2-yl)methoxy]-benzenepropanoic acid

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1374516-07-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₁FO₃

Molecular Weight: 364.41

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent GPR120 (free fatty acid receptor 4; FFAR4) agonist

MDL Number: N/A

PubChem CID: 57522038

SMILES: CC1=CC=C(C=C1)C2=C(C=C(C=C2)F)COC3=CC=C(C=C3)CCC(=O)O

InChi: InChI=1S/C23H21FO3/c1-16-2-7-18(8-3-16)22-12-9-20(24)14-19(22)15-27-21-10-4-17(5-11-21)6-13-23(25)26/h2-5,7-12,14H,6,13,15H2,1H3,(H,25,26)

InChi Key: LPGBXHWIQNZEJB-UHFFFAOYSA-N