TUG Antibody [4A11A6G11] | 32-195

TUG Antibody [4A11A6G11] | 32-195 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Mouse

Homology: N/A

Immunogen: Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3) .

Research Area: Growth Factors

Tested Application: E, WB

Application: Western Blot:1:500 - 1:2, 000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.

Clonality: Monoclonal

Clone: 4A11A6G11

Isotype: IgG1

Conjugate: Unconjugated

Physical State: N/A

Buffer: Purified antibody in PBS containing 0.03% sodium azide.

Concentration: N/A

Storage Condition: Mouse TUG monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: ASPL, RCC17, TUG, UBXD9, UBXN9, Alveolar soft part sarcoma chromosomal region candidate gene 1 proteinTUG, ASPL, ASPS, ASPCR1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.