TWEAK protein | 30R-AT062

TWEAK protein | 30R-AT062 |

Activity Code: ACTIVE

Product Type: Proteins

Product Subtype: Recombinant Proteins

Research Area: Cancer

Short Description: Purified recombinant Human TWEAK protein

Immunogen: N/A

Host: N/A

Specificity: N/A

Cross Reactivity: N/A

Isotype: N/A

IClone: N/A

Species: Human

Residues: Region of TWEAK protein corresponding to amino acids MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH.

Tag/conjugate: N/A

Protein Type: Recombinant

Expression System: E.coli

Grade & Purity: > 98% pure

Methode of Purification: N/A

Source: N/A

Concentration: N/A

Form & Buffer: Lyophilized from 10mM Na3PO4, pH 7.5 with 100mM L-Arginine. Reconstitute in 10mM Na3PO4, pH 7.5 to a concentration of 1.0 mg/ml.

Storage: Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Shipping Information: *Blue Ice*

Applications: User optimized

Bioactivity: Assay #1: The ED50 as determined by the dose-dependent stimulation of IL-8 production by Human PBMC is less than 10 ng/ml. Assay #2: TWEAK weakly induces the death of HT29 cells when cultured in the presence of IFN-gamma. The ED50 for this effect is between 30-45 ng/ml.

Usage Recommendations: N/A

Assay Information: N/A