UBE2L3 Antibody | 19-297

UBE2L3 Antibody | 19-297 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 73-212 of human UBE2L3 (NP_001243284.1) .

Research Area: Cell Cycle, Neuroscience

Tested Application: WB, IHC, IF

Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: U-251MG

Positive Control 2: HL-60

Positive Control 3: K-562

Positive Control 4: HeLa

Positive Control 5: Mouse testis

Positive Control 6: Mouse brain

Molecular Weight: Observed: 18kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: UBE2L3, E2-F1, L-UBC, UBCH7, UbcM4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s) , ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.