Description
UBE2L6 Antibody | 15-139 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human UBE2L6 (NP_004214.1) .
Research Area: Cell Cycle, Neuroscience
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: Jurkat
Positive Control 3: Mouse kidney
Positive Control 4: Mouse liver
Positive Control 5: Mouse lung
Positive Control 6: Mouse spleen
Molecular Weight: Observed: 18kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: UBE2L6, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBCH8, RIG-B
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s) , ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.