UGT3A2 polyclonal Antibody | BS8994

UGT3A2 polyclonal Antibody | BS8994 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: UDP-glucuronosyltransferase isoenzymes (UGTs) catalyze the glucuronidation of small lipophilic molecules, thereby regulating the bioactivity and metabolic fate of a wide range of endogenous compounds and xenobiotics. Glucuronidation increases the polarity of lipophilic molecules and facilitates their entry into aqueous compartments and, ultimately, their excretion. In essence, glucuronidation provides a protective function by terminating or attenuating the biological activity of its substrates. The UGT3A family of isoenzymes are expressed in liver and kidney, and to a lesser, in the gastrointestinal tract. UGT3A2 (UDP glycosyltransferase 3 family, polypeptide A2) is a 523 amino acid single-pass type I membrane protein that belongs to the UDP-glycosyltransferase family. It has been suggested that members of the UGT3A family may have an important role in the metabolism and elimination of ursodeoxycholic acid, a metabolic byproduct of intestinal bacteria.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: UGT3A2 polyclonal Antibody detects endogenous levels of UGT3A2 protein.

Molecular Weight: ~ 75 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: UDP-glucuronosyltransferase 3A2, UDPGT 3A2; UGT3A2; PSEC0073; UNQ842/PRO1780

Immunogen: Recombinant full length Human UGT3A2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: