Uhrf2 Antibody | 15-127

Uhrf2 Antibody | 15-127 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2) .

Research Area: Apoptosis, Cell Cycle

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: Mouse thymus

Positive Control 2: Mouse testis

Positive Control 3: Mouse liver

Positive Control 4: Rat thymus

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 90kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: 2310065A22Rik, AI42627AW214556, D130071B19Rik, Nirf, E3 ubiquitin-protein ligase UHRF2, Np95-like ring finger protein, RING-type E3 ubiquitin transferase UHRF2, nuclear protein 97, nuclear zinc finger protein Np97, ubiquitin-like PHD and RING finger domain-containing protein 2, ubiquitin-like-containing PHD and RING finger domains protein 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein) , and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.