UM-164 | B2246

UM-164 is a potent c-Src/p38 Kinase Inhibitor with In Vivo activity against Triple-Negative Breast Cancer.

UM-164 is a potent c-Src/p38 Kinase Inhibitor with In Vivo activity against Triple-Negative Breast Cancer.

B2246 | UM-164 DataSheet

Alternate Name/Synonyms: 2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]-5-thiazolecarboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 903564-48-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₃₁F₃N₈O₃S

Molecular Weight: 640.68

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent c-Src/p38 Kinase Inhibitor

MDL Number: N/A

PubChem CID: 11714353

SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)NC(=O)C3=CN=C(S3)NC4=NC(=NC(=C4)N5CCN(CC5)CCO)C

InChi: InChI=1S/C30H31F3N8O3S/c1-18-6-7-22(37-27(43)20-4-3-5-21(14-20)30(31,32)33)15-23(18)38-28(44)24-17-34-29(45-24)39-25-16-26(36-19(2)35-25)41-10-8-40(9-11-41)12-13-42/h3-7,14-17,42H,8-13H2,1-2H3,(H,37,43)(H,38,44)(H,34,35,36,39)

InChi Key: ANEBQUSWQAQFQB-UHFFFAOYSA-N