UNC5D Antibody (Center) [APR13950G]

UNC5D Antibody (Center) [APR13950G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-511 amino acids from the Central region of human UNC5D.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 105880

Clone: Polyclonal

Gene Name: UNC5D

Gene ID: 137970

Function: Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity) . Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity) . May play a role in apoptosis in response to DNA damage (PubMed:24691657) . It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068) . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D, UNC5D, KIAA1777, UNC5H4