UNG monoclonal Antibody | MB65609

UNG monoclonal Antibody | MB65609 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, IHC, WB

Application Range: WB 1:2000, IHC 1:150, FLOW 1:100

Background: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: uracil DNA glycosylase

Molecular Weight: 34.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15

Immunogen: Full length human recombinant protein of human UNG (NP_550433) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A