Upar-(His)N, Human, Recombinant | U001

Upar-(His)N, Human, Recombinant | U001 | Gentaur UK, US & Europe Distribution

Background: This protein is a receptor for urokinase plasminogen activator. It is bound to the plasma membrane via a GPI anchor. However, a soluble protein is also produced in some cell types. It plays a role in localizing and promoting plasmin formation by binding both the proprotein and mature forms of urokinase plasminogen activator (U-PA) and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.

Shipping Conditions: dry ice

OEM: N/A

Storage: N/A