Upstream Binding Protein 1 Polyclonal Antibody | BS65961

Upstream Binding Protein 1 Polyclonal Antibody | BS65961 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,

Application: WB,

Application Range: WB=1:500-2000

Background: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity) . Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Upstream Binding Protein 1 Polyclonal Antibody detects endogenous levels of Upstream Binding Protein 1 protein.

Molecular Weight: 56 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1:351-450/540

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: