USH1C Antibody | 14-505

USH1C Antibody | 14-505 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human USH1C (NP_001284693.1) .

Research Area: Apoptosis, Cell Cycle, Neuroscience

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: HeLa

Positive Control 3: Mouse kidney

Positive Control 4: Mouse small intestine

Positive Control 5: Rat kidney

Positive Control 6: N/A

Molecular Weight: Observed: 62kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: USH1C, AIE-75, DFNB18, PDZ-45, PDZ-73, HARMONIN, NY-CO-37, NY-CO-38, PDZ-73/NY-CO-38, Usher syndrome 1C (autosomal recessive, severe) , harmonin, PDZ-73 protein, ush1cpst, deafness, autosomal recessive 18, AIE75

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.