Valacyclovir Hydrochloride Hydrate | 2201

Valacyclovir is a prodrug of Acyclovir (Cat.No. 2200-50, 250) with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain.

Valacyclovir is a prodrug of Acyclovir (Cat.No. 2200-50, 250) with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV).

2201 | Valacyclovir Hydrochloride Hydrate DataSheet

Alternate Name/Synonyms: L-Valine 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxy)ethyl Ester Hydrochloride hydrate; valaciclovir

Appearance: White solid

Formulation: N/A

CAS Number: 124832-27-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₂₀N₆O₄·HCl·xH2O

Molecular Weight: 360.80 (anhydrous basis)

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: H₂O (>20 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An antiviral agent

MDL Number: MFCD01861507

PubChem CID: 60772

SMILES: CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl

InChi: InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1

InChi Key: ZCDDBUOENGJMLV-QRPNPIFTSA-N