VAMP-1/2/3 (D70) polyclonal Antibody | BS2938

VAMP-1/2/3 (D70) polyclonal Antibody | BS2938 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC:1:50~1:200

Background: VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including a- and g-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and Syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exo-cytosis by competing with SNAP 25 and syntaxins for VAMP binding.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: VAMP-1/2/3 (D70) polyclonal Antibody detects endogenous levels of VAMP-1/VAMP-2/VAMP-3 protein

Molecular Weight: ~ 13 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP1; SYB1; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP2; SYB2; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptobrevin-3; VAMP3; SYB3

Immunogen: Synthetic peptide, corresponding to amino acids 40-90 of Human VAMP1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: