Vancomycin Hydrochloride | B1507

Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci. It acts by binding to bacterial cell wall protein precursors, interfering with continuing protein synthesis. Produces a synergism in antimicrobial activity when combined with Cefotaxime or Carbenicillin. Vancomycin resistance in staphylococcal species has recently emerged as a clinical issue.

Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci.

B1507 | Vancomycin Hydrochloride DataSheet

Alternate Name/Synonyms: Vancocin; Lyphocin

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1404-93-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₆₆H₇₅Cl₂N₉O₂₄ • HCl

Molecular Weight: 1485.71

Cell-Permeable?: Yes

Purity: Potency: ≥900 U/mg

Solubilities: PBS (pH 7.2, ~ 5 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A glycopeptide antibiotic

MDL Number: MFCD03613611

PubChem CID: 6420023

SMILES: CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)(C)N)O.Cl

InChi: InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1

InChi Key: LCTORFDMHNKUSG-XTTLPDOESA-N