Additional Information
Short Description: |
VEGFR inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cardiovascular System, Cancer Growth Inhibitors, Growth Factor Receptor Inhibitors |
Alternative Name(s): |
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
443913-73-3 |
Molecular Formula: |
C22H24BrFN4O2 |
Molecular Weight: |
475,4 |
Source: |
Synthetic |
Purity: |
≥98% (HPLC) |
Solubility: |
Soluble in DMSO (30 mg/ml) or EtOH (10 mg/ml) |
Appearance: |
Yellow solid |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
C1=C3C(=CC(=C1OC)OCC2CCN(CC2)C)N=CN=C3NC4=CC=C(Br)C=C4F |
InChI: |
InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) |
InChIKey: |
UHTHHESEBZOYNR-UHFFFAOYSA-N |
Field of Use: |
For in vitro research use only. |
Related Products
Vandetanib | 1751
26
NULL347.00 - NULL675.00
A potent inhibitor of kinase insert domain-containing receptor [KDR/vascular endothelial growth factor receptor (VEGFR) 2] tyrosine kinase activity (IC₅₀ = 40 nM). This compound also inhibits...
26-1751-GEN
Vandetanib (Zactima) | E1KS1046
426
NULL476.00
Vandetanib (Zactima) | E1KS1046 | Gentaur UK, US & Europe Distribution
426-E1KS1046
Vandetanib, >100% Free Base | BC098-500
495
NULL823.00
Vandetanib, >100% Free Base | BC098-500 | Gentaur UK, US & Europe Distribution
495-BC098-500
