VASP (phospho-S238) polyclonal Antibody | BS4723

VASP (phospho-S238) polyclonal Antibody | BS4723 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is a protein of between 46 and 50 kDa that is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: p-VASP (S238) polyclonal Antibody detects endogenous levels of VASP protein only when phosphorylated at Ser238.

Molecular Weight: ~ 40, 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Vasodilator-stimulated phosphoprotein; VASP

Immunogen: Synthetic phosphopeptide derived from human VASP around the phosphorylation site of Serine 238.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Translational Contral elF4 and p70 S6 Kinase,Insulin &Glucose Signaling,