villin1 polyclonal Antibody | BS91439

villin1 polyclonal Antibody | BS91439 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500-1:2,000 ICC:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100

Background: Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: villin1 polyclonal Antibody detects endogenous levels of villin1 protein.

Molecular Weight: 92/46 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: VIL1, VIL, D2S1471, OTTHUMP00000164145, VIL, VIL1, VILI, Villin 1, Villin-1, Villin1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: