Description
VISTA Detection Set (Risk Free) | RF16070 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: VISTA antibodies were raised against the extracellular domain of human VISTA.
Tested Application: E, WB, ICC, IHC-P, Flow, IF
Application: N/A
Specificity: N/A
Purification: Antibodies are supplied as protein A purified IgG1 and IgG2b.
Clonality: Monoclonal
Isotype: IgG1, IgG2b
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS containing 0.02% sodium azide.
Concentration: Antibody 1 mg/mL
Storage Condition: Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Background: VISTA Antibody: VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications
User Note: Optimal dilutions for each application to be determined by the researcher.