VLDLR Antibody (Center) [APR07213G]

VLDLR Antibody (Center) [APR07213G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 amino acids from the Central region of human VLDLR.

Cellular Localisation: Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein

Molecular Weight: 96098

Clone: Polyclonal

Gene Name: VLDLR

Gene ID: 7436

Function: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity) .

Summary: Tissue Location: Abundant in heart and skeletal muscle; also ovary and kidney; not in liver

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: IHC-P--1:100~500 WB--1:2000

Synonyms: Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR