WBP2 Antibody (C-term) [AMM08507G]

WBP2 Antibody (C-term) [AMM08507G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M

Specificity: This WBP2 antibody is generated from a mouse immunized with a recombinant protein between 1-261 amino acids from the C-terminal region of human WBP2.

Cellular Localisation: Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus when phosphorylated.

Molecular Weight: 28087

Clone: Monoclonal

Gene Name: WBP2

Gene ID: 23558

Function: Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation (PubMed:16772533) . In presence of estrogen, binds to ESR1-responsive promoters (PubMed:16772533) . Required for YAP1 coactivation function on PGR activity (PubMed:16772533) . Synergizes with WBP2 in enhancing PGR activity (PubMed:16772533) . Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity) .

Summary: Tissue Location: Ubiquitous.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: WW domain-binding protein 2, WBP-2, WBP2